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Sciex - Mass Spectrometer Systems | Triple Quad 5500+ – QTRAP Ready

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Mass Spectrometer Systems | Triple Quad 5500+ – QTRAP Ready

Engineered to deliver best-in-class quantitative analysis

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The best just got better. The SCIEX Triple Quad 5500+ LC-MS/MS System – QTRAP Ready is equipped to conquer your laboratory’s most complex workflows and opportunities. With this LC-MS/MS system, you have the sensitivity and performance to meet analytical and regulatory demands for low-level trace detection with ease.

Triple Quad LC-MS/MS systems deliver superior quantitative results in a single injection workflow. When you activate the optional QTRAP functionality, your instrument acts as a linear ion trap (LIT). This allows you to acquire even more data from your sample without sacrificing the sensitivity or quality of your multiple reaction monitoring (MRM) analysis. The QTRAP technology incorporates additional scan types, such as MRM³ (MS/MS/MS), Enhanced Product Ion scans (EPI) and many more. The additional scans can run at the same time you are acquiring your MRM, without any impact on performance or quality of data.

The SCIEX 5500+ System is built on a legacy of cutting-edge engineering innovation. The quality and care are evident in the design of this mass spectrometer. The ion path contains multiple unique technological advances that will enable your laboratory to produce superior results.

Whether you are focusing on pharmaceutical drug discovery workflows, clinical research, food and beverage testing, complex environmental analysis, academic studies, or searching for answers from crucial forensic samples, the 5500+ system is equipped to handle the challenge.

The modular framework of the SCIEX 5500+ System enables additional component upgrades to enhance your data. The instrument is compatible with SelexION^® differential mobility separation which delivers exceptional selectivity of isobaric compounds. If your workflow demands low flow rates, the OptiFlow^® Turbo V™ Ion Source is the ideal technology to achieve your goals. Optimized for microflow chromatography, the OptiFlow ion source can further increase sensitivity, improve selectivity and reduce the consumption of solvents and other consumables.

Key Features

QTRAP Ready	Activating your license through a quick and easy process opens up your SCIEX Triple Quad to a world of possibilities with MS/MS confirmation, enhanced selectivity with MRM³, and other valuable scan types.
Turbo V Ion Source	Extraordinary robustness and superior performance across a wide range of compounds.
OptiFlow Turbo V Ion Source	Upgrade to the OptiFlow source for low-flow analysis. It is robust and simple to operate, with a flow-rate range of 1 -200 µL/min.
HED Detector and High Capacity CEM	Increased productivity with fast polarity switching of 5 msec enabling up to 6 orders of magnitude of linear dynamic range.
Scheduled MRM™ Algorithm Pro	With Analyst^® software, maximize the number of MRM transitions to analyze more compounds in a single run without sacrificing precision.
SCIEX OS-MQ Software	Increased MS quantitation productivity with streamlined data processing*

The power and modularity of a QTRAP Ready system

This mass spectrometer will exceed your expectations. It was engineered to address the things that matter to you most: robustness, sensitivity, maximum uptime, maximum productivity and a solid return on your investment.

Turbo V Ionization Source
- Unique source architecture achieves high sensitivity over a wide range of flow rates.
OptiFlow Turbo V Ionization Source
- Boost sensitivity with the OptiFlow Turbo V Ion source. It uses SteadySpray™ Probes to ensure consistency in low-flow applications.
QTRAP Ready
- Activating your license through a quick and easy process opens up your SCIEX Triple Quad to a world of possibilities with MS/MS confirmation, enhanced selectivity with MRM³, and other valuable scan types.
SelexION Differential Mobility Separation
- SelexION technology provides an extra level of selectivity so you can resolve difficult analytes and have more confidence in detection and quantification.
Analyst Software
- Maximize the number of MRM transitions to analyze more compounds in a single run, without sacrificing precision.
SCIEX OS-MQ Software
- The best way to process your data. Intelligent algorithms deliver a high degree of accuracy and certainty, without time-consuming manual data review.

Key Features of the SCIEX Triple Quad 5500+ LC-MS/MS System – QTRAP Ready

Key Features
Mass Range	A range of 5 to 1250 m/z encompasses many compound classes, enabling your organization to test for more analytes and explore your laboratory’s potential
Polarity Switching Time	A switching time of 5 msec in MRM and Scheduled MRM (sMRM) mode increases efficiency, by performing positive and negative ion analysis in the same acquisition, without compromising sensitivity
Dynamic Range	A dynamic range of up to six orders of magnitude encompasses analyte concentrations from low-level trace detection to those in high abundance
Detector Type	A high-energy dynode and multichannel electron multiplier provide you with the highest quality data for every sample acquisition
MRM Acquisition Rate	With an acquisition rate of 500 MRM/sec, even without using Scheduled MRM, the Triple Quad 5500+ QTRAP Ready system can analyze an extensive suite of compound
Scan Speed	At a scan speed of 12,000 Da/sec, this system detects the crucial analytes in your sample without missing a thing
Built-in Devices	A high-precision syringe pump makes it easier to optimize any new compounds you add to your portfolio of test offerings as your laboratory grows

QTRAP Ready

Activate these powerful and versatile scan types.

Regular MRM Quantitation

With QTRAP technology you will still acquire the same high-quality MRM data for your low-level trace detection workflows.

Added Information
- The EPI scan is unique to QTRAP technology. Add a spectral fingerprint to the same MRM acquisition for greater confidence in your data.
See Through the Matrix
- MRM³ is an effective scan solution for the quantification of analytes when high background and interferences make standard MRM quantification difficult.
Unrivaled QQQ Resolution
- This scan is important in the acquisition of accurate molecular weight and to obtain both the value of the charge state and the accurate mass to charge ratio (m/z).
Full Scan Workflows
- This scan type delivers a highly sensitive full scan for the detection of unknown analytes.

Key Workflows

Whether for pharmaceutical analysis or food and environmental testing, the SCIEX Triple Quad 5500+ LC-MS/MS System – QTRAP Ready delivers the high-quality data you need to make decisions.

Regulated Bioanalysis
- The SCIEX 5500+ System delivers quantitative and qualitative results for a broad range of diverse drug products. It achieves impeccable levels of sensitivity and selectivity helps to ensure proper dosage, efficacy, and safety.
Water Quality Testing
- Acquire data that meets the low-level trace detection requirements of drinking and wastewater labs. Increase confidence with unrivaled confirmation scans like EPI for spectral library assurance.
Antibiotics in Food
- Regulations determine the allowed levels of veterinary drugs in food products. These low-level residues are detected easily with MRM workflows. Activate QTRAP functionality to have even more confidence in your results.
Toxins in Food
- This high-throughput workflow for mycotoxin testing is critical to achieving regulatory compliance. Use a combined MRM and QTRAP library workflow to achieve a new level of confidence in your data.
Pesticides
- A variety of complex matrices are involved when testing for pesticides in fruit, vegetables, water, soil and other samples from emerging markets like cannabis. Quantify and confirm large suites of pesticides using these robust workflows.

Accuracy, Simplicity, and Efficiency

Delivering high-quality, accurate data is one of the primary objectives of any laboratory. Invest in the best software to achieve your data quality goals. The SCIEX 5500+ System is powered by Analyst software for simple acquisition setup and SCIEX OS-MQ software for unrivaled, fast, accurate and efficient data review and processing.

Optimised Processing
- SCIEX OS-MQ software introduces your laboratory to a new era of data processing. It was developed to increase your laboratory’s productivity while delivering accurate and high-quality results. The software platform focuses on getting your staff started easily so they can master it quickly.
Automatic Outlier Removal Algorithm
- The algorithm automatically identifies responses that are outside of the calibration curve parameters. It calculates linear regressions and alerts you to any irregularities.
AutoPeak Integration Algorithm
- Improve your workflow efficiency by delivering consistent integration across samples and batches and reducing the need for manual integration. The AutoPeak Integration Algorithm significantly speeds up your data review.
Compliance
- Sample and data integrity are critical when delivering approved results. SCIEX OS-MQ software incorporates electronic audit trails, signatures and the security elements required for compliance with GxP and 21 CFR Part 11 Regulations.
Standard Addition
- SCIEX OS-MQ software incorporates native standard addition, which allows it to perform those vital calculations alongside your integrated analysis.
Enhanced Filtering of Results
- Filter your data your way. Unique filtering functionality and advanced flag rules make it easier than ever to interpret your data and focus on key results.

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